Claritin D (Loratadine and Pseudoephedrine)

Claritin D Review

Claritin-D is used to relieve hay fever and allergy symptoms, including sneezing, runny nose, and red, itchy, tearing eyes. Claritin-D is in a class of medications called antihistamines. It works by blocking histamine, a substance in the body that causes allergic symptoms. Claritin-D may cause less drowsiness than other antihistamines.

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Claritin D Drug Class and Mechanism

Claritin is a type of medication that blocks the action of histamine, a natural substance in your body that is released by your immune system during an allergic reaction.

Claritin D Uses

Loratadine is a drug used to treat allergies, and marketed for its nonsedating properties. It is marketed by Schering-Plough under several trade names such as Claritin, Claritin-D, Claritine, Clarityn, Clarityne or Fristamin depending on the market; by Lek as Lomilan; by Sandoz as Symphoral; by Ranbaxy as Roletra; by Pliva as Rinolan; and by Wyeth as Alavert. It is also available as a generic. In a version marketed as Claritin-D or Clarinase, loratadine is combined with pseudoephedrine, a decongestant; this makes it somewhat useful for colds as well as allergies, but adds a potential side-effect of insomnia, nervousness and anxiety.Adult and CHILD over 6 years: 10 mg daily CHILD 2-5 years: 5 mg daily

Claritin D Side Effects

Serious side effects are not likely to occur with the use of Claritin-D. If you experience any of the following serious side effects, stop taking Claritin-D and contact your doctor immediately or seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); an irregular heartbeat; or seizures. Other, less serious side effects may be more likely to occur. Continue to take Claritin-D and talk to your doctor if you experience dizziness; headache; insomnia; nervousness; nausea, diarrhea, or abdominal discomfort; dry mouth; dry skin or itchiness; or discoloration of urine. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Claritin D Pregnancy

Loratadine; Pseudoephedrine Sulfate 12 Hour Extended Release Tablets: There was no evidence of animal teratogenicity in reproduction studies performed on rats and rabbits with this combination at oral doses up to 150 mg/kg (885 mg/m2 or 5 times the recommended daily human dosage of 250 mg or 185 mg/m2), and 120 mg/kg (1416 mg/m2 or 8 times the recommended daily human dosage), respectively. Loratadine; Pseudoephedrine Sulfate 24 Hour Extended Release Tablets: The combination product loratadine; pseudoephedrine sulfate was evaluated for teratogenicity in rats and rabbits. There was no evidence of teratogenicity in reproduction studies with this combination of the same clinical ratio (1:24) at oral doses up to 150 mg/kg (approximately 5 times the maximum recommended daily human dose on a mg/m2 basis) in rats, and 120 mg/kg (approximately 8 times the maximum recommended daily human dose on a mg/m2 basis) in rabbits. Similarly, no evidence of animal teratogenicity in rats and rabbits was reported at oral doses up to 96 mg/kg of loratadine alone (approximately 75 and 150 times, respectively, the maximum human daily oral dose on a mg/m2 basis). Loratadine; Pseudoephedrine Sulfate 12 and 24 Hour Extended Release Tablets: There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, loratadine; pseudoephedrine sulfate extended release tablets should be used during pregnancy only if clearly needed.

Claritin D Overdose

In the event of overdosage, general symptomatic and supportive measures should be instituted promptly and maintained for as long as necessary. Treatment of overdosage would reasonably consist of emesis (ipecac syrup), except in patients with impaired consciousness, followed by the administration of activated charcoal to absorb any remaining drug. If vomiting is unsuccessful, or contraindicated, gastric lavage should be performed with normal saline. Saline cathartics may also be of value for rapid dilution of bowel contents. Loratadine is not eliminated by hemodialysis. It is not known if loratadine is eliminated by peritoneal dialysis.

Claritin D More Information

This product has been approved for use by the Food and Drug Administration in children age of 6 years and older. Your pediatrician or healthcare professional is your best source of information to determine the appropriate treatment and dosage for your child.